OMRF names new scientific leaders
Congratulations to Agnieszka Borowik on her publication in Function titled: “Skeletal Muscle Nuclei in Muscle are not Post-Mitotic”
Congrats to Dr. Matthew Bubak for receiving both a VA pilot award and an AFAR Glenn Foundation Post-doc Fellowship.
Polish exchange superstar Evelina Voloviceva gave an excellent summary talk of her year in the United States. Congrats to Evelina on her new PhD in Switzerland.
Miller lab postdocs, Aga, Matt, Arik and Jordan all received travel awards for both Experimental Biology and AGE
Welcome New Lab Members!
Michael Taylor, Sandra Rigsby, and Allison Morphis!
Miller lab collaboration gets the cover of Function.
OMRF honors scientists at spring board meeting
The Merrick Award for Outstanding Medical Research was given to Benjamin Miller, Ph.D., an internationally recognized leader in aging research. Miller, a physiologist, seeks to prevent the onset of chronic diseases by slowing the biological process of aging. His current work focuses on whether metformin, the world’s most prescribed diabetes drug, is effective at slowing aging.
The Miller lab is happy to receive their new R01 from NIH titled: Determining the Context Specificity of Metformin Treatment on Muscle Mitochondria and Healthspan.
Congrats to Arik Davidyan for being one of ten recipients of the American Aging Association (AGE) Early Career Scholar for 2022, which is a travel award for the AGE annual meeting.
Congrats to Matt Bubak and Arik Davidyan on their abstract awards from the Cell and Molecular Physiology Section of APS for the Experimental Biology Annual Meeting.
Congrats to Miller lab member Nina Cassidy on getting accepted into the Biomedical Engineering Ph.D. program at Vanderbilt University.
Agnieszka Borowik and Jordan Fuqua Receive Awards
Agnieszka Borowik was awarded the 2022 Drs. Lou Stephenson and Margaret (Peg) Kolka Women in Physiology Postdoctoral Research Award by the APS Environmental & Exercise Physiology Section. Jordan Fuqua received the 2022 American Physiology Society (APS) Underrepresented Minority Postdoctoral Award.
New funding accelerates aging research at OMRF
Miller lab receives an Longevity Impetus Grant in the initial round of funding.
New publication in Function
“A novel stable isotope approach demonstrates surprising degree of age-related decline in skeletal muscle collagen proteostasis”. The co-first authors are former Fleming Scholar Claire Abbott and her Post-doc mentor Dr. Marcus Lawrence.
Welcome Jordan Keast from OSSM Summer Research Fellowship
Welcome 2021 Fleming Scholar Matle Broomfield
Read the featured article from the March 2021 issue of The Physiologist Magazine.
Welcome new post-doc Matt Bubak.
Matt completed his PhD at the University of Kansas.
Kamil Kobak presents poster
Kamil Kobak presents a poster titled “Protein and Ribosomal Turnover in Adult Male Mice” at the AGE virtual meeting.
Congratulations to Arik Davidyan
Congratulations to Arik Davidyan for receiving the Geroscience T32.
Congratulations to Marcus
Congratulations to Marcus for securing a new faculty job. We will miss you.
Congrats to Dr. Josh Butcher on his K01!
Congrats to Dr. Josh Butcher on his K01! We look forward to assisting your progression.
Congrats to Marcus Lawrence
Congrats to Marcus Lawrence for his abstract travel award from the EEP section of APS for EB 2020!
Marcus Lawrence Awarded Postdoctoral Stipend
Marcus Lawrence has been awarded a $50,000 career development stipend from the American Physiological Fellowship.
Fountain of Youth?
Visit to University of Kentucky
A successful and productive visit to the University of Kentucky to work with our collaborators in the labs of Dr. Esther Dupont-Versteegden and Dr. Tim Butterfield. Thank you for hosting.
Congratulations to Jared Gregston & Claire Abbott
Thanks to Marcus Lawrence & Justin Reid who mentored them through the process.
New York Times features a story about a new study from OMRF’s Dr. Ben Miller.
Welcome Fleming Scholars Claire Abbott and Jared Gregston
Jared is a sophomore at the University of Oklahoma majoring in biology with an NGO minor. Jared enjoys running, volunteering, and working part-time as an EMT. Claire is going into her senior year at San Diego State University as a Pre-Medicine, Biology with an emphasis in Evolution and Systematics major, and an Honors Minor. Claire enjoys running and being active, wildlife photography, and playing guitar accompanied with vocals. She hopes to go to medical school and possibly become a dermatologist and dermatopathologist.
Congrats to Justin Reid
Justin Reid successfully competed for the OMRF Trainee Scholarship. It is rare for a first year to obtain this award, so congrats to Justin.
Journal of Gerontology Publications
New Publications The lab has several new publications including the following noteworthy publications from former PhD student Chris Wolff and current PhD student Justin Reid. Both publications will appear in the Journal of Gerontology with a series of papers on targeting mTOR for slowed aging. Congratulations! Reid JJ, Linden MA, Peelor FF, Miller RA, Hamilton KL, Miller BF. Brain Protein Synthesis Rates in the UM-HET3 Mouse Following Treatment with Rapamycin or Rapamycin with Metformin. J Gerontol A Biol Sci Med Sci. 2019. PMID: 30864881 Wolff CA, Reid JJ, Musci RV, Linden MA, Konopka AR, Peelor FF, Miller BF, Hamilton KL. Differential Effects of Rapamycin and Metformin in Combination with Rapamycin on Mechanisms of Proteostasis in Cultured Skeletal Myotubes. J Gerontol A Biol Sci Med Sci. 2019. PMID: 30820523
27th Annual Summer Training Course
The 27th Annual Summer Training Course will be held at Oklahoma Medical Research Foundation from June 22 to June 27, 2019. For more information, please click here.
2019 Oklahoma Geroscience Symposium
The 2019 Oklahoma Geroscience Symposium will be held on April 24, 2019 at the Oklahoma Medical Research Foundation. Please click here for more information.
The TAME trial is big news for aging research. We are excited about the potential for pharmaceutical treatments to treat aging. Establishing a framework to complete such work is critical for our field. We present an opinion about why more research may be needed before pursuing metformin as the drug of choice. Our opinion stems from our concern that it may not be ideal for people who are free of disease, which is an important consideration for treatments that increase Healthspan. To see publication, click here Geroscience 2019 Konopka.
A new publication from our laboratory shows that more data are needed before metformin is prescribed for aging. Our clinical trial demonstrate that metformin can inhibit the positive effects of endurance exercise training on skeletal muscle mitochondria. Mitochondria are intimately related to aging and age-related disease. In addition, first-line recommendations for those at risk for type II diabetes is exercise and metformin. Further research is needed to understand long-term outcomes of metformin in subjects who are not diabetic. https://www.ncbi.nlm.nih.gov/pubmed/30548390
We received funding from the Oklahoma Center for Adult Stem Cell Research (OCASCR) to complete studies using novel approaches to determine the necessity of muscle satellite stem cells for muscle growth. These studies will look at the capacity of muscle to regenerate in the absence of satellite cells. PhD student Jaime Laurin and Staff Scientist Shadi Khademi will be working hard on these projects.
Congratulations to lab member Marcus Lawrence for receiving a T32 Post-doc fellowship in Geroscience. This fellowship is an important career step for Marcus and provides him great resources as he works toward other independent awards.