Publications

Methods to characterize lactate turnover in aging and Alzheimer's disease; The LEAN study. Kemna RE, Kueck PJ, Blankenship A, John CS, Johnson CN, Green ZD, Chamberlain T, Thyfault JP, Mahnken JD, Miller BF, Morris JK. Contemp Clin Trials. 2024 Sep 3:107682. doi: 10.1016/j.cct.2024.107682. Online ahead of print. PMID: 39236780.

Muscle-specific mitophagy: insights into hindlimb and diaphragm responses during health and sepsis. Fuqua JD, Mesquita PHC, Taylor ME, Borowik AK. J Physiol. 2024 Sep 2. doi: 10.1113/JP287151. Online ahead of print. PMID: 39222396.

Age-induced changes in skeletal muscle mitochondrial DNA synthesis, quantity, and quality in genetically unique rats. Musci RV, Fuqua JD, Peelor FF 3rd, Nguyen HVM, Richardson A, Choi S, Miller BF, Wanagat J. Geroscience. 2024 Sep 23. doi: 10.1007/s11357-024-01344-4. Epub ahead of print. PMID: 39312152.

Hyperactive mTORC1/4EBP1 signaling dysregulates proteostasis and accelerates cardiac aging Zarzycka W, Kobak KA, King CJ, Peelor FF 3rd, Miller BF, Chiao YA. Geroscience. 2024 October. doi: 10.1007/s11357-024-01344-4. Epub ahead of print. PMID: 39379739.

Unacylated Ghrelin Protects Against Age-Related Loss of Muscle Mass and Contractile Dysfunction in Skeletal Muscle. Georgescu C, Wren JD, Brooks SV, Miller BF, Ahn B. Aging Cell. 2024 Sep 2:e14323. doi: 10.1111/acel.14323. Online ahead of print. PMID: 39223708

Senolytic treatment does not mitigate oxidative stress-induced muscle atrophy but improves muscle force generation in CuZn superoxide dismutase knockout mice. Borowik AK, Lawrence MM, Peelor FF 3rd, Piekarz KM, Crosswhite A, Richardson A, Miller BF, Van Remmen H, Brown JL. Geroscience. 2024 Jun;46(3):3219-3233. doi: 10.1007/s11357-024-01070-x. Epub 2024 Jan 18. PMID: 38233728; PMCID: PMC11009189.

FGF21 Induces Skeletal Muscle Atrophy and Increases Amino Acids in Female Mice: A Potential Role for Glucocorticoids. Larson KR, Jayakrishnan D, Soto Sauza KA, Goodson ML, Chaffin AT, Davidyan A, Pathak S, Fang Y, Gonzalez Magaña D, Miller BF, Ryan KK. Endocrinology. 2024 Jan 16;165(3):bqae004. doi: 10.1210/endocr/bqae004. PMID: 38244215

Time-restricted feeding improves aortic endothelial relaxation by enhancing mitochondrial function and attenuating oxidative stress in aged mice. Milan M, Brown J, O'Reilly CL, Bubak MP, Negri S, Balasubramanian P, Dhanekula AS, Pharaoh G, Reyff Z, Ballard C, Shi H, Yabluchanskiy A, Rudolph MC, Ungvari Z, Marcinek DJ, Miller BF, Van Remmen H, Tarantini S. Redox Biol. 2024 Jul;73:103189. doi: 10.1016/j.redox.2024.103189. Epub 2024 May 15. PMID: 38788541

Metformin treatment results in distinctive skeletal muscle mitochondrial remodeling in rats with different intrinsic aerobic capacities. Bubak MP, Davidyan A, O'Reilly CL, Mondal SA, Keast J, Doidge SM, Borowik AK, Taylor ME, Volovičeva E, Kinter MT, Britton SL, Koch LG, Stout MB, Lewis TL Jr, Miller BF. Aging Cell. 2024 Jun 24:e14235. doi: 10.1111/acel.14235. Online ahead of print. PMID: 38923664 Free article.

17α-Estradiol alleviates high-fat diet-induced inflammatory and metabolic dysfunction in skeletal muscle of male and female mice. Bubak MP, Mann SN, Borowik AK, Pranay A, Batushansky A, Vieira de Sousa Neto I, Mondal SA, Doidge SM, Davidyan A, Szczygiel MM, Peelor FF 3rd, Rigsby S, Broomfield ME, Lacy CI, Rice HC, Stout MB, Miller BF. Am J Physiol Endocrinol Metab. 2024 Mar 1;326(3):E226-E244. doi: 10.1152/ajpendo.00215.2023. Epub 2024 Jan 10. PMID: 38197793; PMCID: PMC11193529.

Current limitations and future opportunities of tracer studies of muscle ageing. . O’Reilly CL, Bodine SC, Miller BF. J Physiol. 2023 Dec 05. doi: 10.1113/JP285616. Online ahead of print. PMID: 38051758.

Sex Differences in the Skeletal Muscle Response to a High Fat, High Sucrose Diet in Rats. Hulett NA, Knaub LA, Hull SE, Pott GB, Peelor R, Miller BF, Shankar K, Rudolph MC, Reusch JEB, Scalzo RL.Nutrients. 2023 Oct 19;15(20):4438. doi: 10.3390/nu15204438. PMID: 37892512 Free PMC article.

Divergence in aerobic capacity and energy expenditure influence metabolic tissue mitochondrial protein synthesis rates in aged rats. Franczak E, Maurer A, Drummond VC, Kugler BA, Wells E, Wenger M, Peelor FF 3rd, Crosswhite A, McCoin CS, Koch LG, Britton SL, Miller BF, Thyfault JP. Geroscience. 2023 Oct 26. doi: 10.1007/s11357-023-00985-1. Online ahead of print. PMID: 37880490

High-fat diet increases electron transfer flavoprotein synthesis and lipid respiration in skeletal muscle during exercise training in female mice. Batterson PM, McGowan EM, Borowik AK, Kinter MT, Miller BF, Newsom SA, Robinson MM. Physiol Rep. 2023 Oct;11(20):e15840. doi: 10.14814/phy2.15840. PMID: 37857571 Free PMC article.

A large-scale LC-MS dataset of murine liver proteome from time course of heavy water metabolic labeling. Deberneh HM, Abdelrahman DR, Verma SK, Linares JJ, Murton AJ, Russell WK, Kuyumcu-Martinez MN, Miller BF, Sadygov RG. Sci Data. 2023 Sep 19;10(1):635. doi: 10.1038/s41597-023-02537-w. PMID: 37726365 Free PMC article.

Short-term repeated human biopsy sampling contributes to changes in muscle morphology and higher outcome variability. Long DE, Mantuano AJ, Confides AL, Miller BF, Kern PA, Butterfield TA, Dupont-Versteegden EE. J Appl Physiol (1985). 2023 Sep 14. doi: 10.1152/japplphysiol.00441.2023. Online ahead of print. PMID: 37705447

Heterochronic Plasma Transfer: Experimental Design, Considerations, and Technical Challenges. Ansere VA, Bubak MP, Miller BF, Freeman WM. Rejuvenation Res. 2023 Oct;26(5):171-179. doi: 10.1089/rej.2023.0035. Epub 2023 Sep 25. PMID: 37551981 Review.

Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle recovery after disuse atrophy. Fuqua JD, Lawrence MM, Hettinger ZR, Borowik AK, Brecheen PL, Szczygiel MM, Abbott CB, Peelor FF 3rd, Confides AL, Kinter M, Bodine SC, Dupont-Versteegden EE, Miller BF. J Cachexia Sarcopenia Muscle. 2023 Oct;14(5):2076-2089. doi: 10.1002/jcsm.13285. Epub 2023 Jul 14. PMID: 37448295 Free PMC article.

17α-estradiol Alleviates High-Fat Diet-Induced Inflammatory and Metabolic Dysfunction in Skeletal Muscle of Male and Female Mice. Bubak MP, Mann SN, Borowik AK, Pranay A, Batushansky A, Mondal SA, Diodge SM, Davidyan A, Szczygiel MM, Peelor FR, Rigsby S, Broomfield M, Lacy CI, Rice HC, Stout MB, Miller BF. bioRxiv. 2023 Jun 15:2023.05.30.542870. doi: 10.1101/2023.05.30.542870. Preprint. PMID: 37398463 Free PMC article.

Metabolic benefits of 17α-estradiol in liver are partially mediated by ERβ in male mice. Mondal SA, Mann SN, van der Linden C, Sathiaseelan R, Kamal M, Das S, Bubak MP, Logan S, Miller BF, Stout MB.Sci Rep. 2023 Jun 17;13(1):9841. doi: 10.1038/s41598-023-37007-1. PMID: 37330610 Free PMC article.

Absence of Either Ripk3 or Mlkl Reduces Incidence of Hepatocellular Carcinoma Independent of Liver Fibrosis. Mohammed S, Thadathil N, Ohene-Marfo P, Tran AL, Van Der Veldt M, Georgescu C, Oh S, Nicklas EH, Wang D, Haritha NH, Luo W, Janknecht R, Miller BF, Wren JD, Freeman WM, Deepa SS. Mol Cancer Res. 2023 Sep 1;21(9):933-946. doi: 10.1158/1541-7786.MCR-22-0820. PMID: 37204757 Free PMC article

Skeletal and cardiac muscle have different protein turnover responses in a model of right heart failure. Bruns DR, McNair BD, Peelor FF 3rd, Borowik AK, Pranay A, Yusifov A, Miller BF. Geroscience. 2023 Apr 29. doi: 10.1007/s11357-023-00777-7. Online ahead of print. PMID: 37118350

Quantifying label enrichment from two mass isotopomers increases proteome coverage for in vivo protein turnover using heavy water metabolic labeling. Deberneh HM, Abdelrahman DR, Verma SK, Linares JJ, Murton AJ, Russell WK, Kuyumcu-Martinez MN, Miller BF, Sadygov RG. Commun Chem. 2023 Apr 17;6(1):72. doi: 10.1038/s42004-023-00873-x. PMID: 37069333 Free PMC article.

Kinetic proteomics identifies targeted changes in liver metabolism and the ribo-interactome by dietary sulfur amino acid restriction. Jonsson WO, Borowik AK, Pranay A, Kinter MT, Mirek ET, Levy JL, Snyder EM, Miller BF, Anthony TG. Geroscience. 2023 Mar 28. doi: 10.1007/s11357-023-00758-w. Online ahead of print. PMID: 36976488

Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle recovery after disuse atrophy. Fuqua JD, Lawrence MM, Hettinger ZR, Borowik AK, Brecheen PL, Szczygiel MM, Abbott CB, Peelor FF 3rd, Confides AL, Kinter M, Bodine SC, Dupont-Versteegden EE, Miller BF. J Cachexia Sarcopenia Muscle. 2023 Jul 14. doi: 10.1002/jcsm.13285. Online ahead of print. PMID: 37448295

Metabolic benefits of 17α-estradiol in liver are partially mediated by ERβ in male mice. Mondal SA, Mann SN, van der Linden C, Sathiaseelan R, Kamal M, Das S, Bubak MP, Logan S, Miller BF, Stout MB.Sci Rep. 2023 Jun 17;13(1):9841. doi: 10.1038/s41598-023-37007-1. PMID: 37330610

Absence of either Ripk3 or Mlkl reduces incidence of hepatocellular carcinoma independent of liver fibrosis. Mohammed S, Thadathil N, Ohene-Marfo P, Tran AL, Van Der Veldt M, Georgescu C, Oh S, Nicklas EH, Wang D, Haritha NH, Luo W, Janknecht R, Miller BF, Wren JD, Freeman WM, Deepa SS. Mol Cancer Res. 2023 May 19:MCR-22-0820. doi: 10.1158/1541-7786.MCR-22-0820. Online ahead of print. PMID: 37204757

Skeletal and cardiac muscle have different protein turnover responses in a model of right heart failure. Danielle R Bruns, Benjamin D McNair, Frederick F Peelor 3rd, Agnieszka K Borowik, Atul Pranay, Aykhan Yusifov, Benjamin F Miller PMID: 37118350 DOI: 10.1007/s11357-023-00777-7

Quantifying label enrichment from two mass isotopomers increases proteome coverage for in vivo protein turnover using heavy water metabolic labeling. Henock M Deberneh, Doaa R Abdelrahman, Sunil K Verma, Jennifer J Linares, Andrew J Murton, William K Russell, Muge N Kuyumcu-Martinez, Benjamin F Miller, Rovshan G Sadygov Published online 2023 Apr 17. doi: 10.1038/s42004-023-00873-x PMCID: PMC10110577 PMID: 37069333

Kinetic proteomics identifies targeted changes in liver metabolism and the ribo-interactome by dietary sulfur amino acid restriction William O Jonsson, Agnieszka K Borowik, Atul Pranay, Michael T Kinter, Emily T Mirek, Jordan L Levy, Elizabeth M Snyder, Benjamin F Miller, Tracy G Anthony. PMID: 36976488 DOI: 10.1007/s11357-023-00758-w

Low-load blood flow-restricted resistance exercise produces fiber type-independent hypertrophy and improves muscle functional capacity in older individuals Jakob Wang, Anna-Maria Godsk Mogensen, Frederik Thybo, Magnus Brandbyge, Jonas Brorson Jensen, Gerrit van Hall, Jakob Agergaard, Frank Vincenzo de Paoli, Benjamin F Miller, Hans Erik Bøtker, Jean Farup, Kristian Vissing PMID: 36825645 DOI: 10.1152/japplphysiol.00789.2022

17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice. Samim Ali Mondal, Roshini Sathiaseelan, Shivani N Mann, Maria Kamal, Wenyi Luo, Tatiana D Saccon, José V V Isola, Frederick F Peelor 3rd, Tiangang Li, Willard M Freeman, Benjamin F Miller, Michael B Stout. PMID: 36516471 PMCID: PMC9902223 (available on 2024-02-01) DOI: 10.1152/ajpendo.00256.2022

Exercise and mitochondrial remodeling to prevent age-related neurodegeneration. Colleen L O'Reilly, Benjamin F Miller, Tommy L Lewis Jr. PMID: 36519568 PMCID: PMC9829476 DOI: 10.1152/japplphysiol.00611.2022

Skeletal Muscle Nuclei in Mice are not Post-mitotic. Agnieszka K Borowik 1, Arik Davidyan, Frederick F Peelor 3rd, Evelina Voloviceva, Stephen M Doidge, Matthew P Bubak, Christopher B Mobley, John J McCarthy, Esther Dupont-Versteegden, Benjamin F MillerB. PMID: 36569816 PMCID: PMC9772608 DOI: 10.1093/function/zqac059

Fractional Gluconeogenesis: A Biomarker of Dietary Energy Adequacy in a Rat Brain Injury Model. Casey C Curl 1, Anika Kumar 1, Austin J Peck 1, Jose A Arevalo 1, Allison Gleason 1, Robert G Leija 1, Adam D Osmond 1, Justin J Duong 1, Benjamin F Miller 2 3, Michael A Horning 1, George A Brooks 1 PMID: 36557201 PMCID: PMC9781857 DOI: 10.3390/metabo12121163

Proceedings from the Albert Charitable Trust Inaugural Workshop on 'Understanding the Acute Effects of Exercise on the Brain' Jill N Barnes 1, Jeffrey M Burns 2, Marcas M Bamman 3, Sandra A Billinger 2, Sue C Bodine 4, Frank W Booth 5, Patrice Brassard 6, Tameka A Clemons 7, Paul J Fadel 8, Paige C Geiger 9, Swathi Gujral 10, Jacob M Haus 11, Scott E Kanoski 12, Benjamin F Miller 13, Jill K Morris 2, Kristin M S O'Connell 14, David C Poole 15, Darleen A Sandoval 16, J Carson Smith 17, Russell H Swerdlow 2, Shawn N Whitehead 18, Eric D Vidoni 2, Henriette van Praag 19 PMID: 36721393 PMCID: PMC9837736 DOI: 10.3233/BPL-220146

A Genetically Heterogeneous Rat Model with Divergent Mitochondrial Genomes. Samim Ali Mondal 1, Roshini Sathiaseelan 1 2, Shivani N Mann 3, Maria Kamal 4, Wenyi Luo 4, Tatiana D Saccon 1, José V V Isola 1, Frederick F Peelor 3rd 1, Tiangang Li 5, Willard M Freeman 6 7, Benjamin F Miller 1 7, Michael B Stout 1 7 PMID: 36516471 PMCID: PMC9902223 (available on 2024-02-01) DOI: 10.1152/ajpendo.00256.2022

An In Vivo Stable Isotope Labeling Method to Investigate Individual Matrix Protein Synthesis, Ribosomal Biogenesis, and Cellular Proliferation in Murine Articular Cartilage. Kobak KA, Batushansky A, Borowik AK, Lopes EPB, Peelor Iii FF, Donovan EL, Kinter MT, Miller BF, Griffin TM. Function (Oxf). 2022 Feb 25;3(2):zqac008. doi: 10.1093/function/zqac008. eCollection 2022. PMID: 35399495

Mechanotherapy Reprograms Aged Muscle Stromal Cells to Remodel the Extracellular Matrix during Recovery from Disuse. Hettinger ZR, Wen Y, Peck BD, Hamagata K, Confides AL, Van Pelt DW, Harrison DA, Miller BF, Butterfield TA, Dupont-Versteegden EE. Function (Oxf). 2022 Mar 24;3(3):zqac015. doi: 10.1093/function/zqac015. eCollection 2022. PMID: 35434632

Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma. Thadathil N, Selvarani R, Mohammed S, Nicklas EH, Tran AL, Kamal M, Luo W, Brown JL, Lawrence MM, Borowik AK, Miller BF, Van Remmen H, Richardson A, Deepa SS. Aging Cell. 2022 Jul 23. doi: 10.1111/acel.13676. Online ahead of print. PMID: 35869934

Antecedent Metabolic Health and Metformin (ANTHEM) Aging study: Rationale and study design for a randomized controlled trial. Kumari S, Bubak M, Schoenberg HM, Davidyan A, Elliehausen CJ, Kuhn KG, VanWagoner TM, Karaman R, Scofield RH, Miller BF, Konopka AR. J Gerontol A Biol Sci Med Sci. 2021 Dec 2:glab358. doi: 10.1093/gerona/glab358. Online ahead of print. PMID: 34865016

Necroptosis contributes to chronic inflammation and fibrosis in aging liver. Mohammed S, Thadathil N, Selvarani R, Nicklas EH, Wang D, Miller BF, Richardson A, Deepa SS. Aging Cell. 2021 Dec;20(12):e13512. doi: 10.1111/acel.13512. Epub 2021 Nov 11. PMID: 34761505 Free article.

Oklahoma Nathan Shock Aging Center - assessing the basic biology of aging from genetics to protein and function. Van Remmen H, Freeman WM, Miller BF, Kinter M, Wren JD, Chiao A, Towner RA, Snider TA, Sonntag WE, Richardson A. Geroscience. 2021 Oct;43(5):2183-2203. doi: 10.1007/s11357-021-00454-7. Epub 2021 Oct 4. PMID: 34606039 Free PMC article.

Determining the contributions of protein synthesis and breakdown to muscle atrophy requires non-steady-state equations. Kobak KA, Lawrence MM, Pharaoh G, Borowik AK, Peelor FF 3rd, Shipman PD, Griffin TM, Van Remmen H, Miller BF. J Cachexia Sarcopenia Muscle. 2021 Aug 21. doi: 10.1002/jcsm.12772. Online ahead of print. PMID: 34418329

Systemic delivery of a mitochondria targeted antioxidant partially preserves limb muscle mass and grip strength in response to androgen deprivation. Rossetti ML, Dunlap KR, Salazar G, Hickner RC, Kim JS, Chase BP, Miller BF, Gordon BS. Mol Cell Endocrinol. 2021 Sep 15;535:111391. doi: 10.1016/j.mce.2021.111391. Epub 2021 Jul 7. PMID: 34245847

Age-Related Susceptibility to Muscle Damage Following Mechanotherapy in Rats Recovering From Disuse Atrophy. Hettinger ZR, Hamagata K, Confides AL, Lawrence MM, Miller BF, Butterfield TA, Dupont-Versteegden EE. J Gerontol A Biol Sci Med Sci. 2021 Nov 15;76(12):2132-2140. doi: 10.1093/gerona/glab186. PMID: 34181006

A Novel Stable Isotope Approach Demonstrates Surprising Degree of Age-Related Decline in Skeletal Muscle Collagen Proteostasis. Claire B Abbott, Marcus M Lawrence, Kamil A Kobak, Erika Barboza Prado Lopes, Frederick F Peelor, III, Elizabeth J Donald, Holly Van Remmen, Timothy M Griffin, Benjamin F Miller, Function, Volume 2, Issue 4, 2021, zqab028, https://doi.org/10.1093/function/zqab028

Tumor burden negatively impacts protein turnover as a proteostatic process in non-cancerous liver, heart, and muscle, but not brain. Brown JL, Lawrence MM, Borowik A, Oliver L, Peelor Iii FF, Van Remmen H, Miller BF. J Appl Physiol (1985). 2021 May 20. PMID: 34013745 PMCID: PMC8325617

Massage as a Mechanotherapy for Skeletal Muscle. Van Pelt DW, Lawrence MM, Miller BF, Butterfield TA, Dupont-Versteegden EE. Exerc Sport Sci Rev. 2021 Apr 1;49(2):107-114. doi: 10.1249/JES.0000000000000244. PMID: 33720912

The ketogenic diet preserves skeletal muscle with aging in mice. Wallace MA, Aguirre NW, Marcotte GR, Marshall AG, Baehr LM, Hughes DC, Hamilton KL, Roberts MN, Lopez-Dominguez JA, Miller BF, Ramsey JJ, Baar K. Aging Cell. 2021 Apr;20(4):e13322. doi: 10.1111/acel.13322. Epub 2021 Mar 6. PMID: 33675103 Free PMC article.

Physiologic Responses to Dietary Sulfur Amino Acid Restriction in Mice Are Influenced by Atf4 Status and Biological Sex. Jonsson WO, Margolies NS, Mirek ET, Zhang Q, Linden MA, Hill CM, Link C, Bithi N, Zalma B, Levy JL, Pettit AP, Miller JW, Hine C, Morrison CD, Gettys TW, Miller BF, Hamilton KL, Wek RC, Anthony TG. J Nutr. 2021 Apr 8;151(4):785-799. doi: 10.1093/jn/nxaa396. PMID: 33512502

Ribosome biogenesis and degradation regulate translational capacity during muscle disuse and reloading. Figueiredo VC, D'Souza RF, Van Pelt DW, Lawrence MM, Zeng N, Markworth JF, Poppitt SD, Miller BF, Mitchell CJ, McCarthy JJ, Dupont-Versteegden EE, Cameron-Smith D. J Cachexia Sarcopenia Muscle. 2021 Feb;12(1):130-143. doi: 10.1002/jcsm.12636. Epub 2020 Nov 24. PMID: 33231914

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia. Chucair-Elliott AJ, Ocañas SR, Stanford DR, Ansere VA, Buettner KB, Porter H, Eliason NL, Reid JJ, Sharpe AL, Stout MB, Beckstead MJ, Miller BF, Richardson A, Freeman WM. Commun Biol. 2020 Nov 19;3(1):693. doi: 10.1038/s42003-020-01418-x. PMID: 33214681

Cancer cachexia in a mouse model of oxidative stress. Brown JL, Lawrence MM, Ahn B, Kneis P, Piekarz KM, Qaisar R, Ranjit R, Bian J, Pharaoh G, Brown C, Peelor FF 3rd, Kinter MT, Miller BF, Richardson A, Van Remmen H. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1688-1704. doi: 10.1002/jcsm.12615. Epub 2020 Sep 12. PMID: 32918528 Free PMC article.

Exercise-Pharmacology Interactions: Metformin, Statins, and Healthspan. Miller BF, Thyfault JP. Physiology (Bethesda). 2020 Sep 1;35(5):338-347. doi: 10.1152/physiol.00013.2020.PMID: 32783612

Sex differences in changes of protein synthesis with rapamycin treatment are minimized when metformin is added to rapamycin. Wolff CA, Lawrence MM, Porter H, Zhang Q, Reid JJ, Laurin JL, Musci RV, Linden MA, Peelor FF 3rd, Wren JD, Creery JS, Cutler KJ, Carson RH, Price JC, Hamilton KL, Miller BF. Geroscience. 2020 Aug 5. doi: 10.1007/s11357-020-00243-8. Online ahead of print. PMID: 32761290.

Massage as a mechanotherapy promotes skeletal muscle protein and ribosomal turnover but does not mitigate muscle atrophy during disuse in adult rats. Lawrence MM, Van Pelt DW, Confides AL, Hunt ER, Hettinger ZR, Laurin JL, Reid JJ, Peelor FF 3rd, Butterfield TA, Dupont-Versteegden EE, Miller BF. Acta Physiol (Oxf) 229:e13460, 2020.

Muscle from aged rats is resistant to mechanotherapy during atrophy and reloading. Lawrence MM*, Van Pelt DW*, Confides AL, Hettinger ZR, Hunt ER, Reid JJ, Laurin JL, Peelor FF 3rd, Butterfield TA, Miller BF, Dupont-Versteedgen EE. GeroScience. 2021 Feb; 43(1): 65–83. Geroscience Published online 2020 Jun 25. doi: 10.1007/s11357-020-00215-y

Utilization of biomarkers as predictors of skeletal muscle mitochondrial content after physiological intervention and in clinical settings. Groennebaek T, Nielsen J, Jespersen NR, Bøtker HE, de Paoli FV, Miller BF, Vissing K. Am J Physiol Endocrinol Metab. 2020 Jun 1;318(6):E886-E889. doi: 10.1152/ajpendo.00101.2020. Epub 2020 Apr 7. PMID: 32255679

Cancer cachexia in a mouse model of oxidative stress. Brown JL, Lawrence MM, Ahn B, Kneis P, Piekarz KM, Qaisar R, Ranjit R, Bian J, Pharaoh G, Brown C, Peelor FF 3rd, Kinter MT, Miller BF,Richardson A, Van Remmen H. . J Cachexia Sarcopenia Muscle PMID: 32918528 PMCID: PMC7749559

Serum extracellular vesicle miR-203a-3p content is associated with skeletal muscle mass and protein turnover during disuse atrophy and regrowth. Van Pelt DW, Vechetti IJ Jr, Lawrence MM, Van Pelt KL, Patel P, Miller BF, Butterfield TA, Dupont-Versteegden EE. Am J Physiol Cell Physiol PMID: 32639875 PMCID: PMC7500218

Mitochondrial adaptations to exercise do not require Bcl2-mediated autophagy but occur with BNIP3/Parkin activation. Ehrlicher SE, Stierwalt HD, Miller BF, Newsom SA, Robinson MM. FASEB J. 2020 Mar;34(3):4602-4618. doi: 10.1096/fj.201902594RR. Epub 2020 Feb 6. PMID: 32030805

The use of deuterated water for the measurement of protein synthesis. Miller BF, Reid JJ, Price JC, Lin HL, Atherton PJ, Smith K. CORP: .J Appl Physiol (1985). 2020 May 1;128(5):1163-1176. doi: 10.1152/japplphysiol.00855.2019. Epub 2020 Mar 26. PMID: 32213116

Molecular changes associated with spinal cord aging. Geroscience. Piekarz KM, Bhaskaran S, Sataranatarajan K, Street K, Premkumar P, Saunders D, Zalles M, Gulej R, Khademi S, Laurin J, Peelor R, Miller BF, Towner R, Van Remmen H. 2020 Apr;42(2):765-784. doi: 10.1007/s11357-020-00172-6. Epub 2020 Mar 6.PMID: 32144690

Differential Effects of Rapamycin and Metformin in Combination with Rapamycin on Mechanisms of Proteostasis in Cultured Skeletal Myotubes. Wolff CA, Reid JJ, Musci RV, Linden MA, Konopka AR, Peelor FF, Miller BF, Hamilton KL. J Gerontol A Biol Sci Med Sci. 2019. PMID: 30820523

Muscle-specific changes in protein synthesis with aging and reloading after disuse atrophy. Miller BF, Baehr LM, Musci RV, Reid JJ, Peelor FF 3rd, Hamilton KL, Bodine SC. J Cachexia Sarcopenia Muscle. 2019 Dec;10(6):1195-1209. doi: 10.1002/jcsm.12470. Epub 2019 Jul 16. PMID: 31313502 Free PMC Article

Interaction between an SGLT2 inhibitor and exercise training. Metabolism. Linden M.A., Ross T.T., Beebe D.A., Gorgoglione M.F., Hamilton K.L., Miller B.F., Braun B., Esler W.P. 2019. May 24. PMID: 31132381 DOI: 10.1016/j.metabol.2019.05.009

Brain Protein Synthesis Rates in the UM-HET3 Mouse Following Treatment with Rapamycin or Rapamycin with Metformin. Reid JJ, Linden MA, Peelor FF, Miller RA, Hamilton KL, Miller BF. J Gerontol A Biol Sci Med Sci. 2019. PMID: 30864661

Short-term calorie restriction and 17α-estradiol administration elicit divergent effects on proteostatic processes and protein content in metabolically active tissues. Miller B.F., Pharaoh G.A., Hamilton K.L., Peelor F.F., Kirkland J.L., Freeman W.M., Mann S.N., Kinter M., Price J.C., Stout M.B. 2019. J Gerontol A Biol Sci Med Sci. 2019 May 10. PMID: 31074767.

Long-Term Aerobic Exercise Preserves Muscle Mass and Function with Age. Laurin, J.L., Reid, J.J., Lawrence, M.M., and Miller B.F*. 2019. Current Opinions in Physiology. 10:70–74. doi.org/10.1016/j.cophys.2019.04.019

Taming expectations of metformin as a treatment to extend healthspan. Konopka, A. R., & Miller, B. F. (2019).GeroScience. http://doi.org/10.1007/s11357-019-00057-3

Enhanced skeletal muscle regrowth and remodelling in massaged and contralateral non-massaged hindlimb. Miller, B. F., Hamilton, K. L., Majeed, Z. R., Abshire, S. M., Confides, A. L., Hayek, A. M., Hunt, E.R., Shipman, P., Peelor, F.F., Butterfield, T.A. and E.E. Dupont-Versteegden. (2018). The Journal of Physiology, 596(1), 83–103. PMID: 29090454. PMCID: PMC5746529.

Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults. Konopka AR, Laurin JL, Schoenberg HM, Reid JJ, Castor WM, Wolff CA, Musci RV, Safairad OD, Linden MA, Biela LM, Bailey SM, Hamilton KL, Miller BF. Aging Cell. 2018 Dec 11:e12880. doi: 10.1111/acel.12880. PMID: 30548390

A viewpoint on considering physiological principles to study stress resistance and resilience with aging. Miller BF, Seals DR, Hamilton KL. Ageing Res Rev. 2017 Sep;38:1–5. PMID: 28676286 DOI: 10.1016/j.arr.2017.06.004

Mitochondrial proteostasis as a shared characteristic of slowed aging: the importance of considering cell proliferation. Hamilton KL, and Miller BF. The Journal of Physiology. 2017. 595(20):6401-6407. PMID: 28719097 PMCID: PMC5638887

The measurement of protein synthesis for assessing proteostasis in studies of slowed aging. Miller BF, Drake JC, Naylor B, Price JC, Hamilton KL. Ageing Res Rev. 2014 Nov;18:106-11. PMCID: PMC4258117

Assessment of mitochondrial biogenesis and mTORC1 signaling during chronic rapamycin feeding in male and female mice. Drake JC, Peelor FF, Biela LM, Watkins MK, Miller RA, Hamilton KL, Miller BF. J Gerontol A Biol Sci Med Sci. 2013 Dec;68(12):1493–501. PMCID: PMC3814233

A perspective on the determination of mitochondrial biogenesis. Benjamin F Miller, Hamilton KL. Am J Physiol Endocrinol Metab. 2012 Mar 1;302(5):E496–9. PMCID: PMC3311289